منابع مشابه
Cyclosporine A stimulated hair growth from mouse vibrissae follicles in an organ culture model
Hypertrichosis is one of the most common side effects of systemic cyclosporine A therapy. It has been previously shown that cyclosporine A induces anagen and inhibits catagen development in mice. In the present study, to explore the mechanisms of cyclosporine A, we investigated the effects of cyclosporine A on hair shaft elongation, hair follicle cell proliferation, apoptosis, and mRNA expressi...
متن کاملIn vitro Culture and Histological Characterization of Extracted Human Hair Follicles
Hair transplantation surgery is indicated for the patients with male-pattern baldness that is unresponsive to medical treatments. This procedure can be performed in two different approaches. The first one is the strip harvesting technique; a strip of scalp is removed under local anesthesia and then cut into single follicular units, which are then transplanted back into the balding area in order...
متن کاملMethods for the isolation and 3D culture of dermal papilla cells from human hair follicles
The dermal papilla is a cluster of mesenchymal cells located at the base of the hair follicle which have a number of important roles in the regulation of hair growth. As a consequence, in vitro models of these cells are widely used to study the molecular mechanisms which underlie hair follicle induction, growth and maintenance. While dermal papilla from rodent hair follicles can be digested pri...
متن کاملIsolation and Culture of Neural Crest Stem Cells from Human Hair Follicles.
The hair follicle undergoes lifelong cycling and growth. Previous studies have been focused on epithelial stem cells in the hair follicles. Neural crest stem cells (NCSCs) are pluripotent cells that can persist in adult tissues. We have previously demonstrated that human NCSCs can be isolated from hair follicles. Here, we present a protocol to isolate NCSCs from human hair follicles based on th...
متن کاملIsolation of intermediate filament assemblies from human hair follicles
We used developing human hair follicle cells for the isolation of hard alpha-keratin structural components. Intracellular dispersions examined by electron microscopy contained both individual alpha-keratin filaments and the tactoid-like filament assemblies observed in situ organized along subfibrillar arms of macrofibrils. The assemblies of average width 47 nm were composed of closely packed al...
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ژورنال
عنوان ژورنال: Juntendo Medical Journal
سال: 1992
ISSN: 0022-6769,2188-2134
DOI: 10.14789/pjmj.37.535